Dr. Rhonda Patrick’s The “Big 5”
Biomedical scientist · founder of FoundMyFitness
Goal: Cover the highest-impact nutritional bases for long-term health
Dr. Rhonda Patrick is a biomedical scientist who breaks down the research on nutrition and longevity at FoundMyFitness. She calls these five her “Big 5” — the supplements she says deliver roughly 80% of the benefit for 20% of the effort. These are the staples she has publicly described taking; doses are approximate and based on her public statements. See the evidence behind each one below, then add the stack to your own tracker in a tap.
Source: Compiled from FoundMyFitness — Top 5 Supplements. Compiled from publicly available statements. Not affiliated with, endorsed by, or reviewed by the named individual. Not medical advice.
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What’s in it
- 🐟 Omega-3 (EPA/DHA)Strong evidence
- Dose
- ~2 g/day EPA+DHA, split between meals
- When
- With meals (AM & PM)
- 💊 Vitamin D3 + K2Limited evidence
- Dose
- ~4,000 IU D3 with ~100 mcg K2 (MK-7); targets 40–60 ng/mL
- When
- Daily, with a fat-containing meal
- 💊 Multivitamin with folateLimited evidence
- Dose
- One per day, as nutritional insurance
- When
- Daily
- 🪨 Magnesium GlycinateStrong evidence
- Dose
- Sleep-supportive form
- When
- Evening, before bed
- 🥦 Sulforaphane (BrocElite)Limited evidence
- Dose
- Broccoli-sprout compound
- When
- Daily
- 💪 Creatine MonohydrateStrong evidence
- Dose
- ~5 g/day
- When
- Daily
- 🟡 Turmeric / CurcuminStrong evidence
- Dose
- ~1 g/day (added as a daily staple)
- When
- Daily
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