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Spermidine

longevity · Autophagy · anti-aging · cellular renewal · heart

Limited evidence

Spermidine is a polyamine that induces autophagy — the cellular self-cleaning process. Found in wheat germ, aged cheese, and mushrooms. Declining levels are associated with aging.

⏱️ Timing & dosage for Spermidine

Best time to take

Morning with or without food

Suggested dose

1–10mg daily; wheat germ extract is most studied form

✅ Benefits of Spermidine

  • Autophagy induction (cellular self-cleaning)
  • Cardiovascular health
  • Anti-aging effects
  • Immune function
  • Hair growth support

⚠️ Side effects & risks

  • Very safe
  • Research still emerging in humans
  • May cause mild GI discomfort at high doses

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⚕️ Medical Disclaimer: Nothing on Stack Ritual constitutes medical advice. The information provided is for educational purposes only. Always consult your doctor or a qualified healthcare provider before beginning, changing, or stopping any vitamin, supplement, or wellness regimen.