💊 Amino acids · Limited evidence
N-Acetyl L-Cysteine (NAC)
Cysteine amino acid and glutathione precursor. People take it for:
- Glutathione and antioxidant support
- Thinner mucus, mostly shown in lab models
- Lung support in conditions like COPD
Why it works
People take it as a glutathione precursor with antioxidant properties, and for thinner mucus. Given by IV it is well established after acetaminophen overdose, while evidence for cystic fibrosis is mixed and COPD studies point to fewer flare-ups. Absorption by mouth is low, and studies using under about 1,200 mg a day may show little effect.
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How to take N-Acetyl L-Cysteine (NAC)
Suggested dose
600mg
Side effects and risks
- Can cause nausea, vomiting and diarrhea, and has a strong smell and taste
- Has blood-thinning properties, so use caution with bleeding disorders or blood thinners
- May cause low blood pressure when combined with nitroglycerin
N-Acetyl L-Cysteine (NAC) interactions
Works withGlycine
NAC supplies cysteine and glycine supplies the other limiting amino acid for glutathione. Taken together they raise glutathione more than either does alone.
Related supplements
- 💊 TrimethylglycineGlycine with 3 methyl groups attached. Plays a major role in as a methyl donor to supports healthy homocysteine levels.
- 💊 L-Tyrosine (Free-Form)Amino acid for focus under stress
- 🏃 Beta-AlanineMuscle endurance · lactic acid buffer · athletic performance
- 💊 GABACalming amino acid taken for stress and sleep
- 💊 L-Lysine 500mgEssential amino acid often taken for cold sores
- 💊 N-Acetyl-Cysteine (NAC) 600mgCysteine amino acid and glutathione precursor
Medical disclaimer: Nothing on Stack Ritual constitutes medical advice. The information provided is for educational purposes only. Always consult your doctor or a qualified healthcare provider before beginning, changing, or stopping any vitamin, supplement, or wellness regimen.