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Melanotan 1

peptides · UV-free tanning peptide

Moderate evidence

Melanotan 1 is a synthetic analogue of alpha-MSH that stimulates melanin production for tanning without UV exposure. Unlike Melanotan 2, it doesn't significantly cross the blood-brain barrier and has a cleaner side-effect profile. It's FDA-approved as an implant (Scenesse) for a rare sun-sensitivity condition.

⏱️ Timing & dosage for Melanotan 1

Best time to take

2-3x weekly for tanning protocols; as needed

Suggested dose

SubQ, start at 0.5 mg, increase to 1-2 mg once tolerance is established (the FDA-approved implant form is a 16 mg subcutaneous implant for the approved indication)

✅ Benefits of Melanotan 1

  • Produces a tan without UV exposure
  • FDA-approved (as Scenesse) for the sun-sensitivity condition erythropoietic protoporphyria
  • Cleaner side-effect profile than Melanotan 2
  • Potential photoprotection through increased melanin

⚠️ Side effects & risks

  • Outside its FDA-approved implant form, typically self-administered via subQ injection as a research compound -- verify purity/COA
  • Common: nausea and flushing, particularly at higher doses
  • Darkening of existing moles and new mole formation -- monitor for changes; medical supervision recommended

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⚕️ Medical Disclaimer: Nothing on Stack Ritual constitutes medical advice. The information provided is for educational purposes only. Always consult your doctor or a qualified healthcare provider before beginning, changing, or stopping any vitamin, supplement, or wellness regimen.